Abstract. Mobile phones are one of the main sources of man-made electromagnetic radiation (EMR). It is known that EMR causes oxidative stress, increasing the formation of reactive oxygen species (ROS), which disrupts cell function [1–3]. Excessive accumulation of ROS inhibits the activity of antioxidant enzymes and leads to an imbalance between the prooxidant and antioxidant systems.

The aim of the work to investigate the correlations between the activities of key enzymes of the antioxidant system (AOS) under the influence of EMR. Materials and methods. The object of the study was the embryos of the freshwater loach fish (Misgurnus fossilis L.) [4; 5]. The initial material for the study was the experimental data obtained by us [4–6], namely the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPO) under the influence of EMF of different duration (1; 5; 10; 20 min) at the studied stages of embryo development (2; 16; 64; 256; 1024 blastomeres). To perform the correlation analysis, the “Data Analysis” tool of the Microsoft 365 Excel program was used [7].

The results. It was established that under the influence of EMR in loach embryos, a negative correlation was observed between the activities of SOD and CAT, as well as between SOD and GPO, while a positive correlation was found between the activities of GPO and CAT. This nature of the interaction of enzymes indicates insufficient efficiency of the antioxidant system, which contributes to the accumulation of reactive oxygen species (ROS) in cells. Conclusions. It was established that electromagnetic radiation disrupts the coordinated activity of antioxidant enzymes. As a result of this imbalance, the defense mechanisms of the loach embryos weaken, which leads to an increase in the level of oxidative stress.

Keywords: Сorrelation, catalase, superoxide dismutase, glutathione peroxidase, antioxidant system

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