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ECPB 2013, 61(1): 65–69
Clinical physiology and biochemistry

The state of central hemodynamics of young people with elevated and normal blood pressure at different weather types

VADZYUK S., KAHRAMANIAN A.
Abstract

We have selected two groups of male students aged 18–22 for our study (30 in each group). The first (control) group consisted of students whose blood pressure (BP) was at optimal and normal level. The second group consisted of students whose current blood pressure was above normal (systolic blood pressure was above 139 mm Hg.column., and (or) diastolic – above 89 mm Hg.column.

Chest rheography was performed to study central hemodynamics. The survey was carried out at I (favorable) and III (unfavorable) weather types in the mornings. To establish the types of weather we used integrated algorithm of medical forecast assessment by I.I. Grigorieva. Arterial pressure was measured by the Korotkoff method.

The examination of students with high blood pressure showed that the third type of forecast corresponded to the likely increased indices of diastolic and medium dynamic pressures, increased heart rate and end-diastolic pressure of the left ventricle. Also, examinees with elevated blood pressure during weather type III showed reduction in stroke and cardiac indices. A significant increase in total and specific peripheral resistance during the third weather type has led to a decrease in blood flow velocity and fall of left ventricular performance, which was reflected in significantly lower values of acceleration indices, speed, performance and capacity of the left ventricle.

Central hemodynamic parameters of the patients in control group at the first and third weather types did not differ. There was a certain tendency to increased values of blood pressure, peripheral vascular resistance, reduced stroke and cardiac indexes, and indexes of contractility, acceleration, velocity, left ventricular load and maximum speed of blood flow.

Indicators of central hemodynamics in the patients with normal blood pressure compared with the data obtained from patients with high blood pressure were characterized by significantly lower values of peripheral vascular resistance. Especially noticeable difference of central hemodynamics between examinees with high blood pressure and control group was observed during weather type III.

Concluding mentioned above, one of the main mechanisms of meteopathy in young people with high blood pressure is an increasing afterload on left ventricular myocardium due to a significant increase in peripheral resistance. This may be due to the increasing influence of humoral factors in the regulation of the cardiovascular system during bad weather. This was also confirmed by the data obtained earlier in the course of heart rate mathematical analysis of patients with high blood pressure during the third weather type. Conclusions. Circulatory homeostasis maintenance in patients with high blood pressure under unsatisfactory weather conditions was marked by an increase in peripheral vascular resistance along with a reduction in cardiac output.

During medically unsatisfactory weather conditions, the patients with elevated blood pressure experience increase in the afterload on left ventricular myocardium, as evidenced by a decrease in indices of acceleration, velocity of the left ventricle and the maximum speed of blood flow.

Keywords: hypertension, central hemodynamics, types of weather

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